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Science for Living: Can using AI risk prediction in breast cancer screening improve early detection?

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Artificial intelligence is revolutionizing the field of medicine, and researchers at UMass Chan Medical School are investigating how AI tools can enhance breast cancer screening. According to the American Cancer Society, early detection is crucial in improving outcomes for breast cancer patients. Standard mammography, while effective, has limitations, especially in detecting tumors in women with dense breast tissue.

Dr. Mohammed Salman Shazeeb and Dr. Gopal Vijayaraghavan are collaborating on an AI-driven risk assessment model that analyzes routine screening mammograms to estimate a woman’s likelihood of developing breast cancer in the next few years. This tool helps identify women who may benefit from supplemental screening, rather than recommending it for every patient.

In a study involving 145 participants, the AI tool identified four additional cancers through MRI that were missed by mammography alone. Dr. Vijayaraghavan emphasized that while MRI remains the gold standard for detecting many breast cancers, it is not feasible for everyone annually. The AI tool aims to focus resources on high-risk individuals, making early detection more efficient and personalized.

AI models can pick up subtle imaging features that may be overlooked by human eyes, drawing on patterns learned from extensive datasets. While AI tools can process more image features than radiologists can visually, they are designed to augment clinical judgment, not replace it. Human oversight is critical in interpreting AI-generated findings and ensuring their significance.

Although promising, the use of AI-guided risk assessment in clinical care faces challenges such as FDA approval, reimbursement policies, and equitable access. Larger-scale validation studies and real-world implementation data are needed before widespread adoption. Engaging patients in the research process is also crucial, as many are willing to contribute to furthering research on breast cancer screening.

Experts view AI as a supportive tool that can personalize screening based on individual risk factors, rather than a standalone solution. The goal is to enhance early detection of breast cancer, leading to more effective and less invasive treatments. As research progresses, AI tools like this one may pave the way for a more personalized and effective approach to breast cancer screening, combining cutting-edge technology with clinical expertise to benefit women’s health.